Laird Advances DNA Replication Process with New PCR Cycler

Global technology leader Laird (LRD: London) is lowering the barriers-to-entry and increasing service differentiation for both manufacturers and solution providers of medical equipment with the release of a new PCR (Polymerase Chain Reaction) Cycler Evaluation Kit.

 Laird’s new Evaluation Kit enables faster and more reliable results for DNA replication processes. This allows medical equipment manufacturers and solutions providers to offer their customers more reliable and accurate results in less time which allows for shortened drug development times and increased throughput in testing labs.

 For example, when diagnosing hereditary diseases, identifying genetic fingerprints (used in forensic sciences and paternity testing), and detecting or diagnosing infectious diseases, Polymerase Chain Reaction (PCR) is often used to replicate the DNA being tested.  This is an exacting process, often times requiring the rapid heating and cooling of the DNA sample based on a predefined series of temperature steps. Simple temperature controllers can often overshoot set temperature points when ramping at these fast rates.  This can frequently lead to inaccurate test results.

 "The market is evolving toward faster chemistries used in DNA amplification. Too many manufacturers are using simple temperature controllers that are not sophisticated enough to manage fast thermal responses," explains Anders Kottenauer, Senior Vice President of Laird's Engineered Thermal Systems business. He adds, "Use of our new PCR Cycler technology can improve test accuracy and ultimately lead to the detection of new pathogens and treatment solutions.”

 The PCR Cycler Evaluation Kit, identified as model PC-24-TS-58, includes a programmable controller that utilizes an ultrafast thermal feedback loop and two control loops, one for the control side and one for the heat rejection side. These allow the controller to quickly and accurately adjust to the precise temperatures required throughout the process cycle without increasing test time or interfering with the results.

 The controller incorporates alarm features and a port for SD flash memory cards to log temperatures and electric current throughout the duration of DNA amplification.  This verifies that the device is operating effectively and that DNA has been driven to specified temperature set point ranges.

 The evaluation kit includes a thermoelectric assembly, cycling controller and graphical interface.

Comments

Post a Comment

Popular posts from this blog

What is Class I Division 2?

Image
A Class I Division 2 is a location: (1) In which volatile flammable gases, flammable liquid-produced vapors, or combustible liquid-produced vapors are handled, processed, or used, but in which the liquids, vapors, or gases will normally be confined within closed containers or closed systems from which they can escape only in case of accidental rupture or breakdown of such containers or systems or in case of abnormal operation of equipment, or (2) In which ignitable concentrations of flammable gases, flammable liquid-produced vapors, or combustible liquid-produced vapors are normally prevented by positive mechanical ventilation, and which might become hazardous through failure or abnormal operation of the ventilating equipment. Class I Division 2 Classification Class I Division 2 refers to the ANSI/ISA 12.12.01 standard. This standard was previously UL1604 until UL recommended the newer ANSI/ISA standard be used and that all hazardous location products be certified under this standa
Read more

FUSE SIZING CONSIDERATIONS FOR HIGHER EFFICIENCY MOTORS

Image
When selecting the proper fuse for short circuit protection in motor starting applications, it is important to not only ensure that the fuse will not nuisance open during motor start up times, but also that the fuse will coordinate as required with overload relays. When sizing fuses between 125% and 150% of the motor nameplate current, several advantages, including ease of coordination with an overload device, a smaller disconnect, and increased short circuit protection from a lower fuse rating, can be achieved. However, if sizing at this level prevents the motor from starting, it may then be necessary to increase the fuse ampere rating and it then becomes important to know the NEC sizing limitations. As of June 1, 2016, the US Department of Energy has mandated that newly manufactured electric motors will need to meet NEMA Premium® efficiency standards. As motor efficiencies increase, motor locked rotor currents can also be expected to increase. In addition to this, with across-the-lin
Read more

7/8 16UN Connectors that Provide 600 Volts and 15 Amps

TURCK announces new A-Size 3 and 4-pin 7/8 16UN powerfast™ connectors that provide up to 600 Volts and 15 Amps of power. These IP67 rated connectors provide a modular wiring system designed to handle high current applications for machine power distribution, while providing resistance to vibration commonly associated with conveyors, motors and material handling applications. The cordsets are available with a tray rated, exposed run PVC flexlife ® cable, with or without STOOW rating, and 14 AWG wires that allow you to replace hard wiring with a robust, quick disconnect system that saves the time and money spent installing a conduit system. The A-Size powerfast line offers male and female, straight connectors, standard and custom lengths, and pigtails or extensions. To make the system complete, fully encapsulated mating receptacles, with 1/2”-14 NPT mounting threads are available.
Read more