Effortless Flow Chemistry

Knowing immediately if the chemistry is at steady state, converting to the desired product, etc., is essential information when developing a robust process in the shortest possible time. FlowIR™ can be interfaced to any continuous flow reactor system and placed virtually anywhere in the fume hood, where space is precious, ensuring the system is easy to use. Being able to monitor the chemistry in situ ensures the collection of the best possible reaction information, which is typically not the case for conventional offline measurement methods. In addition, not having to extract samples increases personnel safety when dealing with highly toxic, energetic or unstable materials.

The in situ monitoring of a continuous flow reaction by FlowIR™ affords the chemist the ability to know when a process is at steady state, if there is any transient intermediate formation or dispersion characteristics, etc.. With the costs of materials rising significantly, one powerful application of FlowIR™ is the ability to track the dispersion characteristic of reagents. Another key aspect of the small footprint and ergonomic design is the ability to stack multiples of FlowIR™ instruments in the smallest space possible. Along with the powerful iC IR™ analysis software, development chemists are now able to use multiple FlowIR™ systems to follow, for example, the dispersion profiles of several reagents in a multistep, continuous flow synthesis of a complex compound. Without the ability to measure the dispersion profiles in situ and in real time, chemists have to use excessive amounts of very expensive reagents, which ultimately requires an additional process step to remove the excess material from the final product. Stoichiometric control via FlowIR™ is a breakthrough in technology for multistep/reagent synthesis. Until now, no other technology has had such a remarkable ability.

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