Insertion Probes Monitor Bioproduction Process

Stratophase has collaborated with the Centre for Process Innovation (CPI) to develop an insertion probe variant of its Spectrosens system. Enabling real-time monitoring of the bioproduction fermentation process, the multi-output Spectrosens insertion probes track compositional changes and monitor temperature in the liquid.

Multiple discrete readings can be taken simultaneously at numerous locations, providing more reliable measurements and a reduced chance of false positives. As a result, the entire fermentation process can be precisely monitored to ensure reproducibility and clear determination of the desired end-point. The Spectrosens system sensors can be placed throughout the production process and networked via the control and analysis unit.

Using only light at the point of measurement, the sensors are intrinsically safe and spark free, removing any chances of ignition. The insertion probe fits standard ports for dissolved oxygen (DO) and pH probes, enabling ultra-high resolution, optical microchip technology to be applied to existing benchtop and large-scale bioreactor equipment. Other tried and tested applications of the Spectrosens insertion probe include biofuel production and sustainable polymer development. The probe system is currently being trialled at the UK's National Industrial Biotechnology Facility (NIBF).

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